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Circadian heart rhythms in Japanese centenarians
Author(s)Kenichiro Shimizu, Nobuyoshi Hirose, Takayuki Yonemoto
Journal titleJournal of the American Geriatrics Society, vol 47, no 9, September 1999
Pagespp 1094-1099
KeywordsCentenarians ; Cardiovascular systems ; Evaluation ; Cluster analysis ; Japan.
AnnotationAge-associated changes in the circadian rhythm of the heart rate was investigated in fifty Japanese centenarians in this study. The participants, and a control group, underwent 24-hour ambulatory electrocardiogram (Holter) monitoring. The relationship between clinical parameters (activities of daily living (ADL), cognitive function, nutritional status, and present illness) and patterns of heart rate rhythm was investigated. Results revealed circadian changes in the centenarians, which were not related to ADL, cognitive function, nutritional status, present illness, and life expectancy. These findings may indicate that circadian changes are caused by ageing and not dependent on clinical status in very old persons. (AKM).
Accession NumberCPA-991210008 A
ClassmarkBBT: BKK: 4C: 3YB: 7DT

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