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Natural history of pharmacotherapy of older depressed community residents
 — the MRC-ALPHA study
Author(s)K C M Wilson, J R M Copeland, S Taylor
Journal titleBritish Journal of Psychiatry, vol 175, November 1999
Pagespp 439-443
KeywordsDepression ; Drugs ; Living in the community ; Liverpool.
AnnotationDepression in older people is common and has a high mortality, but effective treatment exist. This study aimed to describe drug prescribing in older community residents in relation to depression status. The MRC-ALPHA community cohort aged 65 years and over were interviewed using the Geriatric Mental State examination drug data collected at index interview and at two and four years. Findings showed that antidepressants were used by 10.9% of the depressed population. Benzodiazepines were used frequently, which indicates that it may be misprescribed for treatment of depressive symptoms. Of the antidepressant users, 59.6% took low dose antidepressants for 2 years, had a poor outcome and few drug changes. The study concluded that trends of increasing antidepressant use may have cost implications for primary care groups. (AKM).
Accession NumberCPA-991201228 A
ClassmarkENR: LLD: K4: 84B

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