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Thyroid function, morphology and prevalence of thyroid disease in a population-based study of Danish centenarians
Author(s)Karen Andersen-Ranberg, Bernard Jeune, Mimi H_ier-Madsen
Journal titleJournal of the American Geriatrics Society, vol 47, no 10, October 1999
Pagespp 1238-1243
KeywordsThyroid diseases ; Centenarians ; Denmark.
AnnotationLittle is known about the thyroid in the very old population, and it is not clear whether low prevalence of thyroid auto-antibodies in healthy centenarians is due to ageing or simultaneous disease. This population-based study of Danish centenarians investigated thyroid function, morphology, and aut-oimmunity in relation to physical function. In all, 207 of the 276 eligible centenarians participated and 148 agreed to blood tests. Findings showed that thyroid dysfunction did not seem more prevalent among centenarians than among younger old people. Low serum T3 was related to poor physical function and comorbidity, whereas thyroid auto-immunity was related only to poor physical functioning. Despite atrophy of the thyroid gland, the findings suggest that thyroid function is well preserved in centenarians. (AKM).
Accession NumberCPA-991201215 A
ClassmarkCPT: BBT: 76K

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