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Mortality from dementias and neurodegenerative disorders in people aged 15-64 in England and Wales in 1979-96
Author(s)Azeem Majeed, Petra Lehmann, Liz Kirby
Journal titleBritish Medical Journal, vol 317, 1 August 1998
Pagespp 320-321
KeywordsDementia ; Death rate [statistics] ; Young people ; Adults ; England ; Wales.
AnnotationThere is now good evidence that the new variant of Creutzfeldt-Jakob disease (CJD) first identified in 1996 is caused by exposure to bovine spongiform encephalopathy (BSE). With this knowledge, the authors investigated whether there has been any increase in mortality from dementias and neurodegenerative disorders since 1979. In order to exclude the large numbers of deaths from senile dementia and Alzheimer's disease (AD), over 65s are excluded. 7796 deaths from dementias and neurodegenerative disorders were found, but there was no evidence for any increase in mortality from these causes in 15-64 year olds since 1979. There was, however, a small but statistically significant increase during 1993-1996. Now that the link between BSE and CJD is fairly well established, it is likely that further cases of new variant CJD will be identified in the future. The Office for National Statistics (ONS) will continue to monitor death rates from dementias. Research is also under way to identify any cases of CJD that may have been missed in people aged under 45 dying from dementing illness during 1979-1996. (RH).
Accession NumberCPA-990928208 A
ClassmarkEA: S5: SB: SD: 82: 9 *

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