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Centre for Policy on Ageing | |
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| Dimensionality of Parkinsonian signs in aging and Alzheimer's disease | | Author(s) | David A Bennett, Kathleen M Shannon, Laurel A Beckett |
| Journal title | The Journals of Gerontology Series A: Biological sciences and Medical Sciences, vol 54A, no 4, April 1999 |
| Pages | pp M191-196 |
| Keywords | Parkinson's disease ; Dementia ; Biological ageing ; Longitudinal surveys ; United States of America. |
| Annotation | Parkinsonian signs are commonly found on the neurological examination of older people, and are associated with morbidity and mortality. The extent to which parkinsonian signs in ageing and Alzheimer's disease (AD) cluster in groups typical of Parkinson's disease is examined. The motor portion of the Unified Parkinson's Disease Rating Scale (UPDRS) or a version with minor modifications, was administered to more than 2,800 people as follows: 637 older people with a wide range of neurological conditions participating in the Chicago Health and Aging Project (CHAP), a study of common health problems from a bi-racial community population; 638 relatively healthy and highly educated older people from 25 Catholic communities participating in the Religious Orders Study, a longitudinal clinical-pathologic study of ageing; and 1,546 older people undergoing evaluation for possible dementia at the Rush Alzheimer's Disease Center. Separate factor analyses were performed on each data set, and by gender and race. The grouping of parkinsonian signs is found to be consistent in diverse samples of older people and does not vary substantially across gender or race. (RH). |
| Accession Number | CPA-990825327 A |
| Classmark | CR6: EA: BH: 3J: 7T |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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