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Functional impairment in instrumental activities of daily living
 — an early clinical sign of dementia?
Author(s)Pascale Barberger-Gateau, Colette Fabrigoule, Catherine Helmer
Journal titleJournal of the American Geriatrics Society, vol 47, no 4, April 1999
Pagespp 456-462
KeywordsSelf care capacity ; Mobility ; Dementia ; Screening ; France.
AnnotationCognitive impairment, including dementias, is one of the major disabling factors in older people. The objective of this study was to estimate the predictive value of four instrumental activities of daily living (IADLs) - ability to use the telephone, mode of transportation, responsibility for own medication, and ability to handle finances - on 3-year and 5-year incident dementia. A random sample of French community dwellers aged 65 and over in 37 randomly selected parishes included in the PAQUID (Personnes Agées QUID) study were followed up at 3 years (1,582 subjects) and 5 years (1,283 subjects). A score summing up the number of dependencies at baseline on four IADLs is a predictor of 3-year but not 5-year incident dementia. Increase in the level of dependence between baseline and 3-year follow-up is associated with an increased risk of incident dementia at 5-year follow-up. These four IADLs can help to identify older subjects at high risk of dementia, who should then undergo neuropsychological testing. (RH).
Accession NumberCPA-990825298 A
ClassmarkCA: C4: EA: 3V: 765

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