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Centre for Policy on Ageing | |
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| Prodromal cognitive disorder in Alzheimer's disease | | Author(s) | Jacques Touchon, Karen Ritchie |
| Journal title | International Journal of Geriatric Psychiatry, vol 14, no 7, July 1999 |
| Pages | pp 556-563 |
| Keywords | Dementia ; Cognitive impairment ; At risk ; Self care capacity ; Evaluation ; Screening ; France. |
| Annotation | The incidence of senile dementia is high in the French EUGERIA Study of Cognitive Ageing, and provides an opportunity to examine older people as they cross the borderline between normal functioning and senile dementia. The aim of this study is to examine the evolution of cognitive deficits in Alzheimer's disease (AD) subjects up to the time of diagnosis, in order to trace the disease's pathway, in terms of intellectual functions affected and identify measures which may maximise the screening process. 397 normal older people hypothesised to have an increased risk of developing AD in the third year were retrospectively compared with 150 subjects who had remained free of senile dementia and other psychiatric disorders throughout the study period. Adjusting for effects of age, education and incident illness, significant differences were found between the two groups on a wide range of tests 2 years before diagnosis. For half of these tests, the decline was largely limited to those with low levels of education. Education effects closer to the time of diagnosis were limited to a small number of verbal tasks. The authors have since been involved in a study to determine the effectiveness of screening procedures in general practice. (RH). |
| Accession Number | CPA-990825279 A |
| Classmark | EA: E4: CA3: CA: 4C: 3V: 765 |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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