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Centre for Policy on Ageing | |
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| The impact of behavioral impairment on functional ability in Alzheimer's disease | | Author(s) | Cynthia R Green, Deborah B Marin, Richard C Mohs |
| Journal title | International Journal of Geriatric Psychiatry, vol 14, no 4, April 1999 |
| Pages | pp 307-316 |
| Keywords | Behaviour disorders ; Self care capacity ; Mobility ; Dementia ; United States of America. |
| Annotation | 149 patients meeting NINCDS-ADRDA criteria for probable Alzheimer's disease (AD) were followed for an average of 37.3 months, with follow-up assessments every 6 months. Subjects were seen at two Alzheimer's Disease Research Center Clinics in New York. Measures included the Physical and Self-Maintenance Scale (PSMS) and Instrumental Activities of Daily Living Scale (IADLS) of Lawton and Brody, and the cognitive and non-cognitive sub-scales of the AD Assessment Scale (ADAS). For each patient, the assessment at which they had their most severe non-cognitive symptoms as measured by the non-cognitive part of the ADAS-NC was determined. ADAS-NC scores were correlated with IADLS and PSMS scores at the same assessment and 6 month later. While there was some modest association of ADAS-NC scores with functional impairment using pairwise correlation coefficients, none of the correlations remained significant when severity of cognitive impairment was controlled statistically. Results suggest that behavioural disturbance, while very troubling to caregivers and patients, does not substantially worsen functional ability beyond the contribution of cognitive impairment in AD. (RH). |
| Accession Number | CPA-990825252 A |
| Classmark | EP: CA: C4: EA: 7T |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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