Centre for Policy on Ageing



Towards a science of Alzheimer's disease management — a model based upon current knowledge of retrogenesis
Author(s)	Barry Reisberg, Sunnie Kenowsky, Emile H Franssen
Journal title	International Psychogeriatrics, vol 11, no 1, March 1999
Pages	pp 7-24
Keywords	Dementia ; Symptoms ; Medical care ; Management [care] ; Research Reviews.
Annotation	Investigations have noted increasingly detailed relationships between the progression of Alzheimer's disease (AD) symptomatology and the inverse order of acquisition of skills and behaviours in normal development, hence such processes may be termed as "retrogenesis". The functional stages of AD can be translated into developmental age equivalents that can be used to explain observed changes in the disease. The retrogenesis-based developmental age model can usefully inform an understanding of the general care needs, emotional and behavioural changes, and activity needs of the AD patient. This model must be amended by necessary caveats regarding physical differences, variations in age-associated pathology, differences in social and societal reactions, and differences in background between AD patients and their developmental age "peers". (RH).
Accession Number	CPA-990728213 A
Classmark	EA: CT: LK: QA: 3A:6KC
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...from the Ageinfo database published by Centre for Policy on Ageing.