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Centre for Policy on Ageing | |
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| Is age a negative prognostic indicator in HIV infection or AIDS? | | Author(s) | M J Keller, J M Hausdorff, L Kyne |
| Journal title | Aging: Clinical and Experimental Research, vol 11, no 1, February 1999 |
| Pages | pp 35-38 |
| Keywords | AIDS ; Age groups [elderly] ; Longitudinal surveys ; United States of America. |
| Annotation | To better understand disease progression in older people with human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS), the authors studied patients aged and 50 and over, hospitalised with a diagnosis of HIV or AIDS, January-October 1995. 86 patients (mean age 54.3 years) were identified. Data was collected on: demographics; opportunistic infections (most frequent was pneumocystis carinii in 43%); comorbid disease (hypertension in 38%; other comorbid disease present in fewer than 15%); neurological dysfunction (present in 66%; 30 patients required treatment for delirium), and antiretroviral therapy. In the 30 with delirium, 23 had anaemia, infection, or both. The median length of survival following diagnosis of AIDS was 18.5 months; for HIV, 48 months. Median length of survival in those with AIDS receiving antiretroviral therapy was 22 months, compared with 11 months for those who did not. In contrast to previous studies, these findings suggest that old age may not necessarily be associated with more rapid disease progression and reduced survival times in those with HIV and AIDS. Absence of significant comorbid disease and access to antiretroviral therapy may partly account for longer survival times. (RH). |
| Accession Number | CPA-990715207 A |
| Classmark | CQTT: BB: 3J: 7T |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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