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Centre for Policy on Ageing | |
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Insight in dementia: when does it occur? — evidence for a nonlinear relationship between insight and cognitive status | Author(s) | Orazio Zanetti, Barbara Vallotti, Giovanni B Frisoni |
Journal title | The Journals of Gerontology Series B: Psychological sciences and social sciences, vol 54B, no 2, March 1999 |
Pages | pp P100-P106 |
Keywords | Dementia ; Cognitive impairment ; Assessment procedures for mental patients ; Correlation ; Italy. |
Annotation | Lack of insight or impaired awareness of deficits in patients with dementia has been neglected. This study at the Alzheimer Dementia Unit in Brescia, Italy evaluated insight in a group of demented patients affected by Alzheimer's disease (AD) and assessed their relationship with the cognitive level of disease severity. 69 consecutive patients affected by AD (n=37) and vascular dementia (n=32) with a wide range of cognitive impairment (MMSE=17±6.4) were recruited. Insight was evaluated with the Guidelines for the Rating of Awareness Deficits (GRAD) - specifically targeted to memory deficits - and the Clinical Insight Rating Scale (CIR), evaluating the broader spectrum of insight (reason for visit, cognitive deficits, functional deficits, and perception of progress of disease). In the whole sample, GRAD and CIR were significantly associated with MMSE and with Clinical Dementia Rating Scale respectively. Insight was uniformly high for MMSE scores _24, showed a linear decrease between MMSE scores of 23 and 13, and was uniformly high for MMSE _12. The model of association between insight and cognitive status reflects more closely the observable decline of insight, providing estimates of when decline of insight begins and ends. (RH). |
Accession Number | CPA-990430003 A |
Classmark | EA: E4: DA:4C: 49: 76V |
Data © Centre for Policy on Ageing |
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...from the Ageinfo database published by Centre for Policy on Ageing. |
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