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A preliminary study of dietary aluminium intake and risk of Alzheimer's disease
Author(s)Mary A M Rogers, David G Simon
Journal titleAge and Ageing, vol 28, no 2, March 1999
Pagespp 205-209
KeywordsDementia ; Diet ; Metals ; United States of America.
AnnotationThe previous lack of studies on the relationship between Alzheimer's disease (AD) and consumption of foods containing large amounts of aluminium additives led to this US pilot study of 46 residents of a geriatric centre in Syracuse, NY, 23 with and 23 without newly-diagnosed AD. Next-of-kin were asked to complete information on the resident's medical history, lifestyle behaviour, and dietary intake before admission to the centre. An expanded form of the Health Habits and History Questionnaire was used to determine dietary intake. Consumption of foods containing high levels of aluminium additives was compared between cases and controls. The data from this study suggest that those who consumed food with a high aluminium content had twice the risk of developing AD, although this result could be due to random error, given the small sample size. Intake of pancakes, waffles, biscuits, muffins, cornbread and/or corn tortillas differed significantly between cases and controls. Adjusted odds ratios were also elevated for grain product desserts, American cheese, chocolate pudding or beverages, salt and chewing gum, but not for tea consumption. Larger studies are required to corroborate or refute these preliminary findings. (RH).
Accession NumberCPA-990429009 A
ClassmarkEA: CFD: YMA: 7T

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