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Centre for Policy on Ageing | |
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| Hypertension and cognitive decline | | Author(s) | Robert Stewart |
| Journal title | The British Journal of Psychiatry, vol 174, April 1999 |
| Pages | pp 286-287 |
| Keywords | Hypertension ; Mental ageing ; Dementia ; Research Reviews. |
| Annotation | Significant associations have been reported between cognitive decline, dementia and measures of cardiovascular and cerebrovascular disease. Such findings raise important possibilities for prevention of dementia through reducing the burden of vascular pathology. It is suggested that it may be more useful to investigate the effects of risk factors for vascular disease, rather than clinical vascular disease itself. Hypertension has received considerable attention in this respect, although it is only recently, thanks to findings from prospective population-based research, that the complex interrelationship between blood pressure levels and cognitive decline has begun to be clarified. This article outlines the methodological issues of study design, and measuring exposure and outcome. It summarises some findings from cross-sectional studies; the patterns of association with regard to blood pressure and cognitive performance which have emerged from prospective research; and evidence for mechanisms of association. Thus clear prospective associations between raised blood pressure and later dementia indicate a potentially important avenue for preventive intervention. (RH). |
| Accession Number | CPA-990427213 A |
| Classmark | CQQ: D6: EA: 3A:6KC |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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