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Centre for Policy on Ageing | |
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| Changing perceptions in osteoporosis | | Author(s) | Terence J Wilkin |
| Journal title | British Medical Journal, vol 318, no 7187, 27 March 1999 |
| Pages | pp 862-865 |
| Keywords | Osteoporosis ; Musculoskeletal systems ; Fractures ; Drugs ; Preventative medicine. |
| Annotation | A recent meta-analysis of 11 separate study populations and over 2,000 fractures concluded that bone mineral density "cannot identify individuals who will have a fracture". This article asks why we measure it. Bone density changes little with antiresorptive treatment (hormone replacement therapy - HRT - and biophosphonate drugs), whereas bone turnover falls dramatically. Antiresorptive treatments prevent fracture and will maintain bone density for as long as they are continued, regardless of whether they are given at the menopause or many years later. Since frequency of impact, which rises exponentially with age, is the main risk factor for fracture, treatment should be focused on infirm older people, irrespective of their bone density. (RH). |
| Accession Number | CPA-990424206 A |
| Classmark | CLO: BK6: CUF: LLD: LK2 * |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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