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Centre for Policy on Ageing | |
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| Antibody response to 1995-1996 influenza vaccine in institutionalized and non-institutionalized elderly women | | Author(s) | A M Iorio, A Alatri, B Camilloni |
| Journal title | Gerontology, vol 45, no 1, January/February 1999 |
| Pages | pp 31-38 |
| Keywords | Influenza ; Immunisation ; Older women ; Nursing homes ; Living in the community ; Comparison ; Italy. |
| Annotation | The background to this Italian study is concern about poor responsiveness to influenza vaccination by institutionalised older people. The study compared haemagglutination-inhibiting antibody response after 1995-1996 vaccination (A/Shandong/9/93 -H3N2; A/Taiwan/1/86 - H1N1; B/Panama 45/90) in 80 older women living in a nursing home with that of 51 non-institutionalised women. No differences were found in pre-vaccination status; after vaccination, a significant humoral response was elicited from both groups against all three influenza strains tested. Institutionalised patients' immune response was satisfactory and significantly higher than that observed in non-institutionalised women. Results were confirmed both by a separate analysis of homogeneous subgroups stratified according to the presence in the two cohorts of potential causes of different antibody response (pre-vaccination antibody titre, long-term drug treatment, risk factors for influenza infection, and physical disability) and by logistic regression analysis to adjust immune responses for the different variables. The vaccination is effective; however, post-vaccination antibody response is influenced by different factors directly or indirectly related to residence. (RH). |
| Accession Number | CPA-990215001 A |
| Classmark | CJM: LLF: BD: LHB: K4: 48: 76V |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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