Centre for Policy on Ageing
 

 
Post-menopausal women and osteoporosis: available choices for maintenance of skeletal health
Author(s)John D Termine, Mayme Wong
Journal titleMaturitas, vol 30, no 3, 16 November 1998
Pagespp 241-245
KeywordsOsteoporosis ; Menopause ; Therapeutics ; Drugs.
AnnotationThe therapeutic choices for osteoporosis prevention which are currently available to post-menopausal women are summarised in this article. Data were obtained from randomised clinical trials and epidemiological studies in post-menopausal women, and pre-clinical studies in ovariectomized rats. Results showed that oestrogen combined with progestogen in hormone replacement therapy (HRT) is effective in relieving perimenopausal symptoms and maintaining bone mineral density. However, the increased breast cancer risk associated with long-term HRT use makes it a less desirable option for many women. Selective oestrogen receptor modulators (SERMs) are also effective in maintaining bone density, without stimulating the breast or uterus. (AKM).
Accession NumberCPA-990122403 A
ClassmarkCLO: CC:BD: LL: LLD

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