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Osteoporosis: intervention options
Author(s)Coen Netelenbos
Journal titleMaturitas, vol 30, no 3, 16 November 1998
Pagespp 235-239
KeywordsOsteoporosis ; Menopause ; Therapeutics.
AnnotationOsteoporosis cause major morbidity in post-menopausal women, however, a variety of treatments are available. This paper summarises the most important intervention options for post-menopausal osteoporosis. The inhibitors of bone resorption, which include calcium, the vitamin Ds, bisphosphonates, calcitonins and gonadal steroids have been variously shown to prevent bone loss or to reduce fractures. On the other hand bone formation stimulating agents as fluorides and in the near future parathyroid hormones and analogues must be considered. However, randomised clinical trials with fractures as clinical end-points are only few in number and not present for every suggested treatment. During the last year it has become clear that besides oestrogen, bisphosphonates and now perhaps the selective oestrogen receptor modulators also show a good alternative as intervention option of postmenopausal osteoporosis. (AKM).
Accession NumberCPA-990122402 A
ClassmarkCLO: CC:BD: LL

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