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Previous psychiatric history as a risk factor for late-life dementia
 — a population-based case-control study
Author(s)Brian Cooper, Clive Holmes
Journal titleAge and Ageing, vol 27, no 2, March 1998
Pagespp 181-188
KeywordsDementia ; Registers [elderly] ; Mental disorder ; Correlation ; Southwark.
AnnotationThe hypothesis that risk for dementia in later life is increased by a history of earlier psychiatric illness is tested. Frequency of earlier treated psychiatric illness was established from information on the Camberwell dementia case register over a 2-year period for people aged 60 or over. A matched control group was drawn from Family Health Service Authority (FHSA) files. Of 559 with a clinical diagnosis of dementia, 70 (12.5%) had a history of psychiatric illness long preceding, and apparently unrelated to onset of dementia. When compared with a matched comparison group of dementia register patients who had no recorded psychiatric history, the two groups appeared broadly similar in type of dementia, severity and clinical features. Applying the same procedure to the matched control group, only 19 (3.4%) had a history of treated psychiatric illness before the age of 70. The increase in risk, which was not restricted to Alzheimer's disease (AD) type dementia, appeared to be characteristic of major psychiatric illness, rather than specific for depression. There is a positive association between previous psychiatric history and late-life dementia which is of predictive significance, and merits further research. (RH).
Accession NumberCPA-981208223 A
ClassmarkEA: QKB: E: 49: 82LT

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