Centre for Policy on Ageing



The premature ageing syndromes — insights into the ageing process
Author(s)	C A E Dyer, A J Sinclair
Journal title	Age and Ageing, vol 27, no 1, January 1998
Pages	pp 73-80
Keywords	Biological ageing ; Early.
Annotation	Since the complex interaction of diseases and other external environmental factors makes it difficult to design experimental studies of ageing, the premature ageing syndromes have been advanced as models of ageing. These conditions are characterised by a number of features - such as vascular pathology, cataracts, skin changes and increased cancer rates - although not all features typically associated with ageing are present in all cases. Research in this field allows insight into the nature of the genes that have a role in ageing, and helps to separate the boundary between ageing and age-related disease. This article outlines first the theories of "normal" ageing, and then the clinical features of premature ageing syndromes: progeria, Werner's syndrome, Cockayne's syndrome, Bloom's syndrome, and ataxia telangiectasia. (RH).
Accession Number	CPA-981208216 A
Classmark	BH: 4J
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...from the Ageinfo database published by Centre for Policy on Ageing.