| |
Centre for Policy on Ageing | |
 | |
|
| A prospective study of dementia with Lewy bodies | | Author(s) | Clive G Ballard, John O'Brien, Kath Lowery |
| Journal title | Age and Ageing, vol 27, no 5, September 1998 |
| Pages | pp 631-636 |
| Keywords | Dementia ; Symptoms ; Diagnosis. |
| Annotation | Little is known about the longitudinal course of dementia with Lewy bodies (DLB) and how this differs from Alzheimer's disease (AD). Standardised baseline and annual assessments of cognitive and non-cognitive symptoms are reported in 73 patients with DLB or AD. AD was diagnosed using the NINCDS ADRDA criteria, and DLB was diagnosed with McKeith et al's Operational criteria for senile dementia of the Lewy body type. Cognitive assessment was undertaken using the MMSE (Mini Mental State Examination) schedule, and operationalised definitions were used to diagnose non-cognitive symptoms. 42 patients with DLB and 30 patients with AD were assessed. Of the 19 on whom post mortem examinations had been performed, 18 have had the clinical diagnosis confirmed. DLB patients were significantly more likely to experience visual hallucinations, disturbances of consciousness and parkinsonism at both baseline and at annual assessments. Of DLB patients exposed to neuroleptics, 33% developed sensitivity reactions. The magnitude and pattern of cognitive decline were similar in both groups. (RH). |
| Accession Number | CPA-981119009 A |
| Classmark | EA: CT: LK7 |
Data © Centre for Policy on Ageing |
|
| ...from the Ageinfo database published by Centre for Policy on Ageing. |
| |
|