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The natural history of mental disorder in old age: Alzheimer's disease and depressive illness compared
Author(s)John R Robinson
Journal titleInternational Journal of Geriatric Psychiatry, vol 13, no 9, September 1998
Pagespp 591-600
KeywordsDementia ; Depression ; Death ; Longitudinal surveys ; United Kingdom.
AnnotationDepressive illness (DI) and Alzheimer's disease (AD) are important causes of morbidity in old age and the relationships between these two disorders are uncertain. The aims of this study were to determine if the prognosis of DI differed from that of the general population and to assess if DI could predispose to AD and compare causes of death. A total of 218 patients with AD and 280 patients with DI were followed up for 15 years. Results showed that the prognosis of DI uncomplicated by physical illness at referral was reasonably good and 5-year survival was double that of AD. The rate of occurrence of AD in DI was no greater than in the general population. The higher mortality from cancer in DI than in AD is unexplained but may relate to differences in aetiology of these two disorders. (AKM).
Accession NumberCPA-981112403 A
ClassmarkEA: ENR: CW: 3J: 8

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