Centre for Policy on Ageing



Aging, memory, and mild cognitive impairment
Author(s)	Ronald C Petersen, Glenn E Smith, Stephen C Waring
Journal title	International Psychogeriatrics, vol 9, supplement 1, 1997
Pages	pp 65-70
Keywords	Cognitive processes ; Memory and Reminiscence ; Dementia ; Diagnosis ; United States of America.
Annotation	In recent years, patients who are at high risk for developing Alzheimer's disease (AD) have become a focus of research. In this article, the authors report on a 5-year study of a group of patients with mild cognitive impairment. In following more than 75 of these patients over 5 years, it appeared that approximately 10% to 15% of the subjects developed AD. The cognitive profiles of the patients at their initial diagnosis were evaluated in an attempt to predict who would remain stable and who would develop AD. Certain features of learning and memory performance indicated patients who were more likely to develop AD, but the strongest predictors was their apolipoprotein E status. The patients who possessed an e4 allele were more likely to convert to AD at a more rapid rate than those who were not carriers. The results and similar data from other studies indicate that diagnostic criteria can be defined for patients who are likely to convert to AD. (AKM).
Accession Number	CPA-981001225 A
Classmark	DA: DB: EA: LK7: 7T
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...from the Ageinfo database published by Centre for Policy on Ageing.