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Influences of thyroid stimulating hormone on cognitive functioning in very old age
Author(s)Åke Wahlin, Tarja-Brita Robins Wahlin, Brent J Small
Journal titleThe Journals of Gerontology Series B: Psychological sciences and social sciences, vol 53B, no 4, July 1998
Pagespp P234-P239
KeywordsOver 70s ; Endocrine systems ; Cognitive processes ; Memory and Reminiscence ; Mental speed ; Correlation ; Sweden.
AnnotationThis Swedish study investigated the relationship of thyroxine (T4) and thyroid stimulating hormone (TSH) within normal ranges to cognitive performance in very old age. 200 non-demented participants aged 75 to 96 years were selected from the ongoing Kungsholmen Project, a population survey of ageing and dementia. Tasks assessing episodic memory, verbal fluency, visuo-spatial ability, short-term memory, and perceptual motor speed were examined. Results indicated that T4 was unrelated to performance. However, TSH was positively related to episodic memory performance, and the effects were independent of the influence of age, level of education, and depressive mood symptoms. There was no reliable effect of TSH on verbal fluency, short-term memory, perceptual motor speed, or visuo-spatial functioning. The influence of TSH on episodic memory was interpreted in terms of its potential effects on encoding and consolidation processes. (RH).
Accession NumberCPA-980903236 A
ClassmarkBBK: BKH: DA: DB: DG: 49: 76P

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