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Aging and Alzheimer's disease: lessons from the Nun Study
Author(s)David A Snowdon
Journal titleThe Gerontologist, vol 37, no 2, April 1997
Pagespp 150-156
KeywordsDementia ; Cognitive processes ; Older women ; Centenarians ; Longitudinal surveys ; United States of America.
AnnotationThis article describes the cognitive status of one participant in the Nun Study, a longitudinal study on Alzheimer's disease (AD). Sister Mary, a nun in the Notre Dame convent in Baltimore, Maryland, was a remarkable woman who had high cognitive test scores before her death at 101 years of age. Despite having abundant neurofibrillary tangles and senile plaques, the classic lesions of Alzheimer's disease, her high cognitive status was maintained. Findings from Sister Mary and all 678 participants in the Nun Study may provide unique clues about the aetiology of ageing and Alzheimer's disease, exemplify what is possible in older age, and show how the clinical expression of some diseases may be averted. (AKM).
Accession NumberCPA-980813401 A
ClassmarkEA: DA: BD: BBT: 3J: 7T

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