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Centre for Policy on Ageing | |
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Tardive dyskinesia in a chronically institutionalized population of elderly schizophrenic patients
— prevalence and association with cognitive impairment | | Author(s) | William Byne, Michael Parella, Rebecca Adams |
| Journal title | International Journal of Geriatric Psychiatry, vol 13, no 7, July 1998 |
| Pages | pp 473-479 |
| Keywords | Mental disorder ; Drugs ; Schizophrenia ; Psychogeriatric patients ; Long term ; Evaluation ; United States of America. |
| Annotation | Tardive dyskinesia (TD) is a late emerging side effect of typical antipsychotics. Chronically hospitalised geriatric inpatients with schizophrenia are at particular risk for both TD and cognitive impairment, but have been insufficiently studied. Neither has the relationship between TD and cognitive impairment been dealt with adequately in this population. In this US study, cognitive status was measured by the Mini-Mental State Examination (MMSE), and the Modified Simpson Dyskinesia Scale was used to assess prevalence of TD, and the relationship between the manifestations of TD in various body regions, and other potentially related variables. Prevalence of TD was 60%, and increased with age, but was not related to current antipsychotic or anticholinergic regimen. Mean MMSE score did not differ between groups of patients with and without TD. Cognitive impairment and TD both increase with age. However, TD alone does not account for the severity of cognitive impairment in this population. This study provides further support for the hypothesis that the correlation between TD and cognitive impairment holds primarily for the orofacial manifestations of TD. (RH). |
| Accession Number | CPA-980810008 A |
| Classmark | E: LLD: ELK: LF:E: 4Q: 4C: 7T |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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