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Predicting survival in patients with Alzheimer's disease living in the community
Author(s)Sally Freels, Donna Cohen, Todd Semla
Journal titleJournal of Mental Health and Aging, vol 2, no 2, Summer/Fall 1996
Pagespp 115-124
KeywordsDementia ; Living in the community ; Death ; United States of America.
AnnotationThe aims of this US study were to identify patient and caregiver factors that predicted length of survival following initial outpatient evaluation in patients with Alzheimer's disease living in the community, and to test the adequacy of the proportional hazards model for survival analysis. Results showed that mental status at the time of diagnosis or evaluation was a significant independent predictor of length of survival. Patients with one caregiver had a lower risk of death than those with multiple caregivers, and patients taking psychotropic drugs had a higher risk of death than those on other or no drugs. However, significant interactions with time were observed, suggesting that hazard rates were not proportional. The study concluded that the proportional hazards regression model, which has been used in all survival research on Alzheimer's disease, may not be appropriate for analysing mortality. (AKM).
Accession NumberCPA-980515213 A
ClassmarkEA: K4: CW: 7T

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