Centre for Policy on Ageing



Natural history of Alzheimer's disease and other dementias — findings from a population survey
Author(s)	Hedda Agüero-Eklund
Publisher	Karolinska Institute; Stockholm Gerontology Research Center, Stockholm, 1998
Pages	59 pp plus appendices
Source	Stockholm Gerontology Research Center, Box 6401, 113 82 Stockholm, Sweden.
Keywords	Dementia ; Over 70s ; Death ; Longitudinal surveys ; Sweden ; Theses.
Annotation	The aim of this doctoral thesis was to examine the natural history of different types of dementia in a very old population. Five studies were performed using data from the Kungsholmen project, a population-based study on ageing and dementia in Stockholm, Sweden that includes subjects aged 75 years and over. Both prevalent and incident dementia cases, as well as cross-sectional and longitudinal analyses were used. The results supported the hypothesis that the onset of dementia is variable. Shorter survival was related to male gender, advanced age, low education, comorbidity and functional disability at baseline. Accelerated cognitive decline was predicted by higher initial cognitive functioning, greater functional disability, and having Alzheimer's disease. Different dementia types were found to have similar survival rates but different prognostic predictors.
Accession Number	CPA-980304413 B
Classmark	EA: BBK: CW: 3J: 76P: 6KG
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