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Centre for Policy on Ageing | |
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| The efficacy and cost effectiveness of vaccination against influenza among elderly persons living in the community | | Author(s) | K L Nichol, K L Margolis, J Wuorenma |
| Journal title | The New England Journal of Medicine, vol 331, no 12, 22 September 1994 |
| Pages | pp 778-784 |
| Keywords | Influenza ; Immunisation ; Cost effectiveness ; Living in the community ; United States of America. |
| Annotation | Despite recommendations, more than half of older Americans do not receive an annual vaccination against influenza. The rate of vaccination and the occurrence of influenza and its complications in the Minneapolis-St Paul area were examined in each of three seasons: 1990/91, 1991/92 and 1992/93. Each cohort included more than 25,000 over 65s. Immunisation rates ranged from 45% to 58%. Although the vaccine recipients had more co-existing illnesses at baseline than those who did not receive the vaccine, during each influenza season vaccination was associated with a reduction in the rate of hospitalisation for pneumonia and influenza (by 48% to 57%) and for all acute and chronic respiratory conditions (by 27% to 39%). Vaccination was also associated with a 37% reduction in the rate of hospitalisation for congestive heart failure during the 1991/92 season when influenza A was epidemic. Costs of hospitalisation for all types of illnesses were lower in the vaccinated group during 1991/92 (range of reduction 47% to 66%) and for acute and chronic respiratory conditions and congestive heart failure in 1990/91. Vaccination was also associated with reductions of 39% to 54% in mortality from all causes during the three influenza seasons. (RH). |
| Accession Number | CPA-980108234 A |
| Classmark | CJM: LLF: WEC: K4: 7T * |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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