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Centre for Policy on Ageing | |
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| Ageing and cognitive decline in people with Down's syndrome | | Author(s) | Wilma C S Jordens, Heleen M Evenhuis, Cees G C Janssen |
| Journal title | The British Journal of Developmental Disabilities, vol 43, part 2, no 85, July 1997 |
| Pages | pp 79-84 |
| Keywords | Cognitive impairment ; Dementia ; Ageing process ; Assessment procedures for mental patients ; Cross sectional surveys ; Netherlands. |
| Annotation | Due to an increased life expectancy, adults with Down's syndrome are nowadays suffering from conditions that could not be observed before. Dementia is common in older people with Down's syndrome, with prevalences of about 5% with 41-45 year olds, increasing to about 45% with 56-60 year olds. With nearly all those with Down's syndrome, dementia turns out to be Alzheimer's disease (AD). It has been found that AD occurs 10-15 years earlier in those with Down's syndrome than those without. In a cross-sectional Dutch study of 46 people with Down's syndrome and 48 matched people with intellectual disability due to other causes, aged between 10 and 50 years, data were gathered using the Dementia Questionnaire for Mentally Retarded Persons measuring cognitive and social functions associated with dementia. A decline with age of the cognitive functioning of those with Down's syndrome relative to the controls was expected, but clear evidence for this linearity has not been found. The results suggest that the onset of cognitive decline in those with Down's syndrome before the age of 50 is at least questionable. (RH). |
| Accession Number | CPA-980106223 A |
| Classmark | E4: EA: BG: DA:4C: 3KB: 76H * |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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