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Centre for Policy on Ageing | |
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Learning and retention in preclinical and early Alzheimer's disease | Author(s) | Ellen Grober, Claudia Kawas |
Journal title | Psychology and Aging, vol 12, no 1, March 1997 |
Pages | pp 183-188 |
Keywords | Dementia ; Memory and Reminiscence ; Learning capacity ; Cognitive processes ; Evaluation. |
Annotation | Accelerated forgetting has been proposed as the first sign in pre-clinical and early Alzheimer's disease (AD).The authors investigated learning and retention in participants who later developed AD with free and cued selective reminding (FCSR), a test which maximises learning by inducing deep semantic processing, and by controlling study and test conditions. AD patients in the pre-clinical stage recalled significantly fewer words than did matched control participants, indicating an impairment of learning. Nonetheless, patients' retention was identical to that of control participants, whose retention was still perfect. Thus, a retention deficit is not present in pre-clinical AD, when hallmark learning deficit can be documented. Detection of pre-clinical and very early AD may be best accomplished by using robust learning tests that control cognitive processing. |
Accession Number | CPA-971120248 A |
Classmark | EA: DB: DE: DA: 4C |
Data © Centre for Policy on Ageing |
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...from the Ageinfo database published by Centre for Policy on Ageing. |
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