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Effects of serum vitamin B12 and folate status on episodic memory performance in very old age
 — a population-based study
Author(s)Ake Wahlin, Robert D Hill, Bengt Winblad
Journal titlePsychology and Aging, vol 11, no 3, September 1996
Pagespp 487-496
KeywordsVitamins ; Memory and Reminiscence ; Over 70s ; Performance ; Correlation.
AnnotationThe authors examined the relationship between low levels of serum vitamin B12 and folic acid, separately or combined, and episodic memory performance in very old age. Participants with low serum vitamin values were compared with a control group matched for age and educational level. Participants (N=250) were selected from a group of non-demented, community-dwelling people aged 75-96. Episodic memory was tested by means of a free recall and recognition of slowly and rapidly presented words. Results indicated a deterioration in both free recall and recognition as a function of serum vitamin status. However, no linear effects of vitamin levels on memory were observed, indicating that vitamin B12 and folic acid status may affect memory only among individuals at the low end of the distribution. The authors speculate that the vitamin-related memory deficit may reflect encoding problems, possibly due to alterations in brain metabolism.
Accession NumberCPA-971120214 A
ClassmarkCFE: DB: BBK: 5H: 49

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