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Quality of life in patients with Alzheimer's disease as reported by patient proxies
Author(s)S M Albert, C Del Castillo-Castaneda, M Sano
Journal titleJournal of the American Geriatrics Society, vol 44, no 11, November 1996
Pagespp 1342-1347
KeywordsDementia ; Quality of life ; Evaluation ; Family care ; United States of America.
AnnotationThe question whether quality of life (QOL) in older people with dementia can be elicited reliably from patient proxies was examined in this study. An instrument was developed, which measured patient activity and affect, and was tested on formal and informal caregivers of 130 patients with Alzheimer's disease (AD). Results showed that QOL ratings were reliably elicited. Family and institutional caregivers differed only in reports of opportunity for patient activity. Frequency of activities declined with increasing severity of dementia. The frequency of negative affects increased and positive affects declined with increasing severity of dementia, but correlations were weak. High QOL, defined by frequent activity and positive affect, was evident in a quarter of the sample. In multivariate models, functional and cognitive status independently predicted QOL among community-resident older adults; only absence of antipsychotics was related to QOL among older people in nursing homes. The authors concluded that although the subjective world of patients with dementia may not be accessible, readily observable behaviours offer a basis for assessing QOL. (AKM).
Accession NumberCPA-970812223 A
ClassmarkEA: F:59: 4C: P6:SJ: 7T

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