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Centre for Policy on Ageing | |
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Site variability in a multisite geriatric depression trial | Author(s) | Gary W Small, Lon S Schneider, S H Hamilton, Alexander Bystritsky |
Journal title | International Journal of Geriatric Psychiatry, vol 11, no 12, December 1996 |
Pages | pp 1089-1095 |
Keywords | Depression ; Geriatric out-patients clinics ; Drugs ; Evaluation ; Clinical surveys ; United States of America. |
Annotation | The authors studied differences in outcome and characteristics among 29 clinical sites of a multisite, double-blind antidepressant (fluoxetine) trial for geriatric depression. Results obtained suggest that individual practitioners may have vastly different clinical experiences on large, multisite trials for geriatric depression. Interrater reliability, subject selection, recruitment, inadequate or fixed dosing, few patients per site, brief study duration, heterogeneity of geriatric depression, financial incentive and characteristics of individual sites may contribute to response variability. |
Accession Number | CPA-970421028 A |
Classmark | ENR: L6G: LLD: 4C: 3G: 7T |
Data © Centre for Policy on Ageing |
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...from the Ageinfo database published by Centre for Policy on Ageing. |
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