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Centre for Policy on Ageing | |
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European herbs and cholinergic activities
— potential in dementia therapy | | Author(s) | Nicolette Perry, Gudrun Court, Natalie Bidet, Jenny Court |
| Journal title | International Journal of Geriatric Psychiatry, vol 11, no 12, December 1996 |
| Pages | pp 1063-1069 |
| Keywords | Dementia ; Therapy ; Alternative medicine ; Clinical surveys. |
| Annotation | The authors investigated plants reputed in herbal encyclopaedias to enhance memory or alleviate mental disorder for cholinergic activities, since this transmitter system has been implicated in memory and dementia. Of three plants with reputed memory enhancing properties (rosemary, sage and balm), extracts of sage inhibited the brain enzyme in a concentration dependant manner. Crude alcoholic extracts of wormwood, balm and angelica displaced nicotine binding to the nicotinic receptor in a concentration dependant manner. Components of these plants may be relevant in relation to dementia therapy, since there is a loss of nicotinic receptors in Alzheimer's disease and related disorders, and stimulation of the nicotinic receptor leads to increased receptor numbers. |
| Accession Number | CPA-970421025 A |
| Classmark | EA: LO: LK3: 3G |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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