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Lifestyle for Brain Health (LIBRA)
 — a new model for dementia prevention
Author(s)Olga J G Schiepers, Sebastian Kohler, Kay Deckers
Journal titleInternational Journal of Geriatric Psychiatry, vol 33, no 1, January 2018
PublisherWiley, January 2018
Pagespp 167-175
Sourcehttp://www.orangejournal.org
KeywordsHealth [elderly] ; Social characteristics [elderly] ; Dementia ; Cognitive impairment ; At risk ; Evaluation ; Observation ; Measurement ; Preventative medicine ; Longitudinal surveys.
AnnotationModifiable risk factors for dementia were identified and compiled in a systematic review. The `Lifestyle for Brain Health' (LIBRA) score, reflecting someone's potential for dementia prevention, was studied in a large longitudinal population-based sample with respect to predicting cognitive change over an observation period of up to 16 years. The score was calculated at baseline for 949 participants aged 50-81 years from the Maastricht Ageing Study. The predictive value of LIBRA for incident dementia and cognitive impairment was examined by using Cox proportional hazard models and by testing its relation with cognitive decline. The score predicted future risk of dementia, as well as risk of cognitive impairment. A one-point increase in LIBRA score related to 19% higher risk for dementia and 9% higher risk for cognitive impairment. LIBRA predicted rate of decline in processing speed, but not memory or executive functioning. The score may help in identifying and monitoring risk status in dementia prevention programmes by targeting modifiable, lifestyle-related risk factors. (JL).
Accession NumberCPA-180302219 A
ClassmarkCC: F: EA: E4: CA3: 4C: 4AA: 3R: LK2: 3J

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