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Centre for Policy on Ageing | |
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Usefulness of data from magnetic resonance imaging to improve prediction of dementia
— population-based cohort study | | Author(s) | Blossom C M Stephan, Christophe Tzourio, Sophie Auriacombe |
| Journal title | BMJ 2015:350:h2863.doi, 22 June 2015 |
| Pages | 11 pp |
| Source | http://www.bmj.com/content/350/bmj.h2863 |
| Keywords | Dementia ; Diagnosis ; Screening ; Longitudinal surveys ; France. |
| Annotation | 1721 people aged 65 and over without dementia who underwent a magnetic resonance imaging (MRI) scan at baseline and with known dementia status over 10 years' follow-up were part of the Dijon MRI study cohort from the Three Cities Study, France. During the 10 years of follow up, there were 119 confirmed cases of dementia, 84 of which were Alzheimer's disease (AD). The study found that data from MRI do not significantly improve discrimination performance in prediction of all cause dementia beyond a model incorporating demographic, cognitive, health, lifestyle, physical function, and genetic data. There were, however, statistical improvements in reclassification, prognostic separation, and some evidence of clinical utility. (RH). |
| Accession Number | CPA-150626021 A |
| Classmark | EA: LK7: 3V: 3J: 765 * |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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