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Utility of the Addenbrooke's Cognitive Examination
 — revised for the diagnosis of dementia syndromes
Author(s)Zoe Terpening, Nicholas J Cordato, Ilana J Hepner
Journal titleAustralasian Journal on Ageing, vol 30, no 3, September 2011
Pagespp 113-118
Sourcewww.wileyonlinelibrary.com
KeywordsDementia ; Diagnosis ; Assessment procedures for mental patients ; Geriatric out-patients clinics ; Evaluation ; Australia.
AnnotationThe utility of the Addenbrooke's Cognitive Examination - Revised (ACE-R) as a screening tool for dementia was evaluated in a prospective audit of 122 patients (82 with dementia, 40 with no dementia) referred to a Sydney cognition clinic. An ACE-R cut-off score of 84/100 provided an optimal balance of sensitivity, specificity and positive predictive value (0.85, 0.80 and 0.90 respectively) in identifying patients with dementia. In this sample, the ACE-R was a superior tool to the Mini Mental State Examination (MMSE) in patients with higher levels of education (10 or more years of formal schooling) but not in patients with lower levels of education. Patients misclassified by the instrument had evidence of high levels of education, focal executive dysfunction, medical comorbidities, significant vascular disease and polypharmacology. The ACE-R is a useful screening tool for detecting the presence of dementia in a cognition clinic setting. However, caution may be warranted in some patient populations. (RH).
Accession NumberCPA-121102215 A
ClassmarkEA: LK7: DA:4C: L6G: 4C: 7YA

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