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Temporal relationship between handgrip strength and cognitive performance in oldest old people
Author(s)Diana G Taekema, Carolina H Y Ling, Susan E Kurrle
Journal titleAge and Ageing, vol 41, no 4, July 2012
Pagespp 506-512
Sourcehttp://ageing.oxfordjournals.org/ http://www.bgs.org.uk/
KeywordsPhysical capacity ; Musculoskeletal systems ; Octogenarians ; Mental ageing ; Cognitive processes ; Cognitive impairment.
AnnotationCognitive decline and muscle weakness are prevalent health conditions in older people. The present study aimed to test the hypothesis that cognitive decline precedes muscle weakness, and to analyse the temporal relationship between cognitive performance and handgrip strength in the oldest old. 555 subjects, all aged 85 years at baseline, were included into this population-based study over four years. Handgrip strength was measured at age 85 and 89 years. A neuropsychological test battery was also carried out to assess global cognitive performance, attention, processing speed and memory at baseline and repeated at age 89 years. Associations between handgrip strength and cognitive performance were analysed by repeated linear regression analysis adjusted for common confounders. At both ages 85 and 89 years, better cognitive performance was associated with higher handgrip strength except for attention. There was no longitudinal association between baseline handgrip strength and cognitive decline except for global cognitive performance. Better cognitive performance at age 85 years was associated with slower decline in handgrip strength after adjustment for common confounders. In conclusion, baseline cognitive performance was associated with decline in handgrip strength, whereas baseline handgrip strength was not associated with cognitive decline. The results suggest that cognitive decline precedes the onset of muscle weakness in the oldest old. (JL).
Accession NumberCPA-120814010 A
ClassmarkBI: BK6: BBM: D6: DA: E4

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