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Centre for Policy on Ageing | |
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Tuberculosis in ageing
— high rates, complex diagnosis and poor clinical outcomes | | Author(s) | Luis Pablo Cruz-Hervert, Lourdes García-García, Leticia Ferreyra-Reyes |
| Journal title | Age and Ageing, vol 41, no 4, July 2012 |
| Pages | pp 488-495 |
| Source | http://ageing.oxfordjournals.org/ http://www.bgs.org.uk/ |
| Keywords | Tuberculosis ; Diagnosis ; Public health ; Statistics ; Ageing process ; Mexico. |
| Annotation | Worldwide the frequency of tuberculosis among older people almost triples that observed among young adults. The purpose of the present study was to describe clinical and epidemiological consequences of pulmonary tuberculosis among older people. Study participants from Southern Mexico with a cough lasting more than two weeks were screened between March 1995 and February 2007. Information on clinical and mycobacteriological data (isolation, identification, drug-susceptibility testing and IS6110-based genotyping and spoligotyping) was collected from individuals with bacteriologically confirmed pulmonary tuberculosis. Patients were treated in accordance with official norms and followed to ascertain treatment outcomes, retreatment, and vital status. 893 tuberculosis patients were older than 15 years of age; of these, 147 (16.5%) were 65 years of age or older. Individuals aged 65 years or over had significantly higher rates of recently transmitted and reactivated tuberculosis. Older age was associated with treatment failure and/or death due to tuberculosis adjusting for sociodemographic and clinical variables. In conclusion, community-dwelling older individuals participate in chains of transmission indicating that tuberculosis is not solely due to the reactivation of latent disease. Untimely and difficult diagnosis and a higher risk of poor outcomes even after treatment completion emphasise the need for specific strategies for this vulnerable group. (JL). |
| Accession Number | CPA-120814007 A |
| Classmark | CJT: LK7: RC: 3Y: BG: 7TY |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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