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Centre for Policy on Ageing | |
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| Validation and diagnostic accuracy of the Alzheimer's questionnaire | | Author(s) | Michael Malek-Ahmadi, Kathryn Davis, Christine Belden |
| Journal title | Age and Ageing, vol 41, no 3, May 2012 |
| Pages | pp 396-399 |
| Source | http://ageing.oxfordjournals.org/ http://www.bgs.org.uk/ |
| Keywords | Dementia ; Cognitive impairment ; Diagnosis ; Instruments ; Measurement ; Evaluation. |
| Annotation | Accurately identifying individuals with cognitive impairment is difficult. The purpose of this study was to determine the diagnostic accuracy of the Alzheimer's questionnaire (AQ) in identifying individuals with mild cognitive impairment (MCI) and Alzheimer's Disease (AD) Utilising a case-control design, 300 AD, 100 MCI and 100 cognitively normal (CN) older adults between the ages of 53 and 93 from a neurology practice and a brain donation programme had the AQ administered to an informant. Diagnostic accuracy was assessed through receiver-operating characteristic analysis, which yielded sensitivity, specificity and area under the curve (AUC). The AQ demonstrated high sensitivity and specificity for detecting MCI and AD. AUC values also indicated high diagnostic accuracy for both MCI and AD. Internal consistency of the AQ was also high. The study concludes that the AQ is a valid informant-based instrument for identifying cognitive impairment, which could be easily implemented in a clinician's practice. It has high sensitivity and specificity in detecting both MCI and AD and allows clinicians to quickly and accurately assess individuals with reported cognitive problems. (JL). |
| Accession Number | CPA-120511008 A |
| Classmark | EA: E4: LK7: YW4: 3R: 4C |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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