Centre for Policy on Ageing



Risk factors for dementia in patients over 65 with diabetes
Author(s)	Niraj M Parikh, Robert O Morgan, Mark E Kunik
Journal title	International Journal of Geriatric Psychiatry, vol 26, no 7, July 2011
Pages	pp 749-757
Source	http://www.interscience.wiley.com/journal/gps
Keywords	Diabetes ; 65-69 age group ; At risk ; Dementia ; Longitudinal surveys.
Annotation	This retrospective longitudinal study examined risk factors for developing dementia in diabetic patients. The study used a national cohort of US veterans with diabetes aged 65 years or more to examine incidence of dementia over two years. A multivariable Cox regression model was used to estimate risk of developing dementia associated with sociodemographic factors, use of diabetes medications, and duration of diabetes. In all, 377,838 patients were studied. Over the two year follow-up, 14,580 (3.85%) were diagnosed with dementia. Major risk factors for dementia included increased old age, being non-white, Southern residence and having diabetes for five years or more. There was a reduced hazard ratio (HR) for dementia with use of an oral hypoglycaemic agent and HMG-CoA reductase inhibitors. There was no change in HR with insulin use. The risk factors established by this study have important implications that warrant further investigation. (JL).
Accession Number	CPA-110822010 A
Classmark	CPD: BBE: CA3: EA: 3J
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...from the Ageinfo database published by Centre for Policy on Ageing.