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Centre for Policy on Ageing | |
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The effect of cognitive impairment on the predictive value of multimorbidity for the increase in disability in the oldest old
— the Leiden 85-plus Study | | Author(s) | Yvonne M Drewes, Wendy P J den Elzen, Simon P Mooijaart |
| Journal title | Age and Ageing, vol 40, no 3, May 2011 |
| Pages | pp 352-357 |
| Source | http://ageing.oxfordjournals.org/ http://www.bgs.org.uk/ |
| Keywords | Octogenarians ; Physical disabilities ; Multiple disabilities ; Chronic illness ; Cognitive impairment ; Observation ; Longitudinal surveys ; Netherlands. |
| Annotation | The purpose of this Dutch study was to investigate the predictive value of multimorbidity for the development of disability in the general population of very old people and the role of cognitive impairment in this association. The research was part of the Leiden 85-plus Study, an observational prospective cohort study with 5 years of follow-up and running from 1997 to 2004. Disability in activities of daily living (ADL) was measured annually for 5 years with the Groningen Activity Restriction Scale. Multimorbidity was defined as the presence of two or more chronic diseases at age 85 years. Cognitive function was measured at baseline with the mini-mental state examination (MMSE). At baseline participants with multimorbidity had higher ADL disability scores compared with those without. Stratified into four MMSE groups, ADL disability increased over time in all groups, even in participants without multimorbidity. Multimorbidity predicted accelerated increase in ADL disability in participants with MMSE of 28_30 points, but not in participants with lower MMSE scores. Concludes that the predictive value of multimorbidity for the increase in ADL disability varies with cognitive function in very old people. In very old people with good cognitive function, multimorbidity predicts accelerated increase in ADL disability. This relation is absent in very old people with cognitive impairment. (JL). |
| Accession Number | CPA-110621007 A |
| Classmark | BBM: BN: BY: CI: E4: 4AA: 3J: 76H |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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