| |
Centre for Policy on Ageing | |
 | |
|
Pilot study of a three-step diagnostic pathway for young and old patients with Parkinson's disease dementia
— screen, test and then diagnose | | Author(s) | Sarah H M Robben, Monique J M Sleegers, Paul L J Dautzenberg |
| Journal title | International Journal of Geriatric Psychiatry, vol 25, no 3, March 2010 |
| Pages | pp 258-265 |
| Source | http://www.interscience.wiley.com/journal/gps doi: 10.1002/gps.2331 |
| Keywords | Parkinson's disease ; Dementia ; Screening ; Diagnosis ; Pilot. |
| Annotation | In a a prospective investigator-blinded study to pilot a three-step diagnostic model for young and old patients with Parkinson's disease dementia (PDD), the authors developed a screening questionnaire for patients with Parkinson's disease (PD) and their caregivers. Further, patients were subjected to three screening instruments (Montreal Cognitive Assessment (MoCA), Frontal Assessment Battery (FAB), Addenbrooke's Cognitive Examination-revised (ACE-R)) and a detailed neuropsychological examination (NPE). Based on the NPE, patients were divided in a PD (without dementia) and a PDD-group. 41 PD patients, aged 37-94 years, participated in this study. Patients were divided into a young group of 22 aged under 65 and an old group of 19 aged 65+. In the young group (PDD, n = 5) the patient-screening questionnaire predicted PDD with a sensitivity/specificity of 100.0%/94.1%; in the old group (PDD, n = 10) the proxy-screening questionnaire predicted PDD with a sensitivity/specificity of 88.9%/66.7%. In the young group, ACE-R had the largest Area Under the Curve (AUC) 0.88 (0.70-1.00); in the old group MoCA (AUC 1.00). However, the three instruments did not differ significantly. It seems feasible and efficient to use three consecutive diagnostic steps for PDD: (1) a screening questionnaire; (2) if positive: MoCA, FAB or ACE-R as screening instrument; and (3) if positive, a detailed NPE for diagnosing PDD. (KJ/RH). |
| Accession Number | CPA-100423202 A |
| Classmark | CR6: EA: 3V: LK7: 4UC |
Data © Centre for Policy on Ageing |
|
| ...from the Ageinfo database published by Centre for Policy on Ageing. |
| |
|