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Centre for Policy on Ageing | |
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Interventions to achieve long-term weight loss in obese older people
— a systematic review and meta-analysis | | Author(s) | Miles D Witham, Alison Avenell |
| Journal title | Age and Ageing, vol 39, no 2, March 2010 |
| Pages | pp 176-184 |
| Source | http://www.ageing.oxfordjournals.org http://www.bgs.org.uk doi:10.1093/ageing/afp251 |
| Keywords | Obesity ; Weight ; Exercise ; Clinical surveys ; Literature reviews. |
| Annotation | The prevalence of obesity is rapidly increasing on older adults. Information is required about what interventions are effective in reducing obesity and influencing health outcomes for people aged 60+. In a systematic review and meta-analysis, 13 databases were searched, earliest date 1966 to December 2006, including Medline, CINAHL, PsychINFO, the Cochrane Index and EMBASE. Studies were included with participants' mean age 60+ and mean body mass index (BMI) 30kg/m² or more, with outcomes at a minimum of 1 year. Data were independently extracted by two reviewers and differences resolved by consensus. Nine eligible trails were included. Study interventions targeted diet, physical activity and mixed approaches. Populations included patients with coronary artery disease, diabetes mellitus and osteoarthritis. Meta-analysis (7 studies) demonstrated a modest but significant weight loss of 3kg ((95% confidence interval (CI) 5.1-0.9) at 1 year. Total cholesterol (4 studies) did not show a significant change: -0.36 mmol/l (95% CI -0.75 to 0.04). There was no significant change in high density lipoprotein, low density lipoprotein, or triglycerides. In one study, recurrence of hypertension or cardiovascular events was significantly reduced (hazard ratio 0.65, 95% CI 0.50-0.85). Six-minute walk test did not significantly change in one study. Health-related quality of life (HRQoL) significantly improved in one study but did not improve in a second study. Although modest weight reductions were observed, there is a lack of high-quality evidence to support efficacy of weight loss programmes for older people. (RH). |
| Accession Number | CPA-100407215 A |
| Classmark | CSA: 4X6: CEA: 3G: 64A |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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