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Impact of interval from breast conserving surgery to radiotherapy on local recurrence in older women with breast cancer
 — retrospective cohort analysis
Author(s)Rinaa S Punglia, Akiko M Saito, Bridget A Neville
Journal titleBritish Medical Journal, vol 340, no 7746, 13 March 2010
Pagesp 581
Sourcewww.bmj.com doi: 10.1136/bmj.c845
KeywordsOlder women ; Cancer ; Surgery ; Therapeutics ; Longitudinal surveys ; United States of America.
AnnotationDoes the length of time between breast conserving surgery and the start of radiotherapy affect the risk of local recurrence in older women with breast cancer? This a summary of a paper published on bmj.com, which found that an interval from surgery to radiotherapy of more than 6 weeks was associated with an increase in local recurrence. Each additional day to start of radiotherapy was associated with the risk of recurrence. Previous studies have had mixed results; but using the US population-based Surveillance, Epidemiology and End Results - Medicare linked database, the results of the present study suggest that the relation between interval to radiation and local recurrence is continuous. Participants for this retrospective cohort analysis were 18,050 women aged 65+ with stage 0-II breast cancer who received breast conserving surgery and radiotherapy but not chemotherapy. (RH).
Accession NumberCPA-100325203 A
ClassmarkBD: CK: LKA: LL: 3J: 7T *

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