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Centre for Policy on Ageing | |
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Myocardial infarction and stroke associated with diuretic based two drug antihypertensive regimens
— population based case-control study | | Author(s) | Inbal Boger-Megiddo, Susan R Heckbert, Noel S Weiss |
| Journal title | British Medical Journal, no 7741, 6 February 2010 |
| Pages | p 303 |
| Source | www.bmj.com BMJ 2010;340:b5479 |
| Keywords | Drugs ; Hypertension ; Stroke ; Heart disease ; Correlation. |
| Annotation | What is the association of several commonly used two drug antihypertensive treatment regimens with myocardial infarction and stroke incidence? In relatively low risk patients with hypertension, the use of diuretics plus calcium channel blockers was associated with a higher risk of myocardial infarction than the use of diuretics plus beta blockers or diuretics plus angiotensin converting enzyme inhibitors of angiotensin receptor blockers. Current US guidelines recommend low dose d diuretics as a first line of pharmacological treatment for uncomplicated hypertension. However, many patients with hypertension require a second medication to control blood pressure. In this summary of a study (published on bmj.com), the use of diuretics plus calcium channel blockers was associated with a higher risk of myocardial infarction than the other commonly used two drug combinations. (RH). |
| Accession Number | CPA-100212203 A |
| Classmark | LLD: CQQ: CQA: CQH: 49 * |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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