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Prescribing safely in elderly psychiatric wards
 — survey of possible drug interactions
Author(s)Akshya Vasudev, Richard Harrison
Journal titlePsychiatric Bulletin, vol 32, no 11, November 2008
Pagespp 417-418
Sourcehttp://pb.rcpsych.org
KeywordsDrugs ; Psychogeriatric units ; Cross sectional surveys.
AnnotationA cross-sectional survey of patient drug prescriptions on two elderly psychiatric wards was carried out to estimate the potential of drug-drug interactions. Two standardised databases, British National Formulary (BNF; British Medical Association & Royal Pharmaceutical Society of Great Britain, 2007) and UptoDate (www.uptodate.com), were employed. Results showed that a majority (96%) of drug prescriptions in our study could potentially cause drug-drug interactions. Most patients were on multiple drugs (on average eight drugs per patient). There was poor concordance between the two databases: BNF picked up fewer cases of potential drug-drug interactions than UptoDate (43 v.152 instances) and they also estimated the potential for hazardousness differently. Polypharmacy is common in elderly psychiatric patients and this increases the possibility of a drug-drug interaction. Estimating the risk of interactions depends on a sound knowledge in therapeutics and/or referring to a standardised source of information. The results of this study question the concordance of two well-referenced databases. (KJ/RH).
Accession NumberCPA-091209214 A
ClassmarkLLD: LDM: 3KB

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