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Do depressive symptoms predict mortality in older people?
Author(s)Philip D St John, Patrick R Montgomery
Journal titleAging & Mental Health, vol 13, no 5, September 2009
PublisherTaylor & Francis, September 2009
Pagespp 674-681
Sourcehttp://www.tandfonline.com
KeywordsDepression ; Symptoms ; Death ; Living in the community ; Correlation ; Canada.
AnnotationDepressive symptoms are common in older people and may predict mortality. This study uses data taken from the Manitoba Study of Health and Aging (MSHA), Canada, to determine: if depressive symptoms predict mortality; if there is a gradient in this effect; and which depressive factors predict mortality. In 1991-1992, 1751 community dwelling older people sampled from a population-based registry, were interviewed. Depressive symptoms were measured using the CES-D scale (Center for Epidemiologic Studies - Depression), age, gender, the Modified Mini-Mental State Examination (MMSE), self-rated health, and functional status. Time to death was the main outcome measure for these analyses. Those scoring 16+ on the CES-D were considered depressed. To determine if a gradient was present, the CES-D was treated as a continuous variable. Four depressive factors from the CES-D (depressed affect, positive affect, somatic, and interpersonal) were analysed. Cox regression models were constructed. Results showed that the mortality in those with depressive symptoms was higher in those without depressive symptoms (Hazard Ratio of 1.71, p < 0.001, Log rank test). In multivariable models, this association was no longer significant after accounting for self-rated health and functional status. There was a gradient in risk of mortality across the range of the CES-D. Somatic factors, depressed affect, and positive affect were all associated with mortality in bivariate analyses, but not in multivariable models adjusting for functional status. Interpersonal factors were not associated with mortality. Depressive symptoms predict mortality in older people. (RH).
Accession NumberCPA-091109211 A
ClassmarkENR: CT: CW: K4: 49: 7S

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