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Centre for Policy on Ageing | |
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Vascular risk factors and cognitive function among 3763 participants in the Hypertension in the Very Elderly Trial (HYVET)
— a cross-sectional analysis | | Author(s) | Ruth Peters, Nigel Beckett, Françoise Forette |
| Journal title | International Psychogeriatrics, vol 21, no 2, April 2009 |
| Pages | pp 359-368 |
| Source | http://www.journals.cambridge.org/ipg |
| Keywords | Cardiovascular diseases ; Blood pressure ; Hypertension ; Assessment procedures for mental patients ; Clinical surveys ; Cross sectional surveys. |
| Annotation | The Hypertension in the Very Elderly Trial (HYVET) was a double blind placebo-controlled trial of anti-hypertensive treatment and recruited only those who had hypertension who were aged 80+ and were without a diagnosis of dementia at baseline. Systolic blood pressure had to be in the range 160-199 mmHg and diastolic pressure <110 mmHg. Cognitive function was assessed at baseline using the Mini Mental State Examination (MMSE) prior to randomisation into the trial. Also collected at baseline was information relating to sociodemographic, clinical, cardiovascular and biochemical factors which may impact upon cognitive function. This paper reports on the baseline cognitive function data from the HYVET trial and its relationship to these factors. The mean age of the 3763 HYVET participants who had full cognitive function data at baseline was 83.6 years; 60% were female. The median MMSE score at baseline was 26 and, in multivariate analyses, higher at younger age, with male gender, higher educational level, having higher creatinine, higher total cholesterol and lower high-density lipoprotein cholesterol. This is the first such study to examine a large number of very old people with hypertension, and it shows some similar patterns to those seen in young-old groups. (KJ/RH). |
| Accession Number | CPA-090825236 A |
| Classmark | CQ: BKL: CQQ: DA:4C: 3G: 3KB |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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