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Centre for Policy on Ageing | |
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| Characteristics and health status change over 6 months in people with moderately severe to severe Alzheimer's disease in the UK | | Author(s) | Gill Livingston, Cornelius Katona, Clément François |
| Journal title | International Psychogeriatrics, vol 18, no 3, September 2006 |
| Pages | pp 527-538 |
| Keywords | Dementia ; Health [elderly] ; Mental health [elderly] ; Health services ; Usage [services] ; Longitudinal surveys ; London ; South East England. |
| Annotation | Until recently, attention and treatment strategies have focused mainly on patients in the early phases of Alzheimer's disease (AD). This study aimed to collect information on moderately severe and severe AD (Mini Mental State Examination, MMSE score <15) in terms of epidemiological, clinical and economic characteristics and disease change in the later stages of AD, and to compare this specific AD population over 6 months with those in the earlier stages. This descriptive analysis recruited institutionalised patients and patients living in the community in London and the South East. Sub-group analyses at baseline and 6 months were performed using the study population from the London and South East Region Alzheimer's Disease (LASER-AD) Study. Data from a range of clinical scales, a quality of life (QoL) scale and a resource utilisation questionnaire were analysed. People with moderately severe or severe AD are a heterogeneous group with varying Qol, cognitive and functional disabilities, neuropsychological symptoms and relatively low health care resource consumption. This patient group continued to decline but progression of the disease was observed only in some domains. Even at the later stages of AD, patients show varying rates of decline. Improved knowledge about the characteristics and progression of the disease reveal that moderately severe and severe patients cannot be regarded as beyond help and have the potential to experience varying and even high levels of QoL. (RH). |
| Accession Number | CPA-090825006 A |
| Classmark | EA: CC: D: L: QLD: 3J: 82L: 82Z |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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